The Commission on Human Medicines advises ministers on the protection, efficacy and quality of medicinal products. For COVID-19 vaccines, the CHM has a COVID-19 Vaccines Safety Surveillance Methodologies Expert Working Group and a COVID-19 Vaccines Benefit Risk Expert Working Group. Cerebral venous sinus thrombosis happens when the brain’s venous sinuses or the smaller veins draining into them are partially or fully blocked by a blood clot. As a end result, the oxygen supply to nerve cells may be impaired and blood cells can leak into the brain tissue causing damage to the mind .

For vaccines which have a two-dose regimen, safety begins 14 days after the primary dose, and seven to 14 days after the second dose. There are 24 opposed event reviews in eleven yr olds who doubtless acquired the Pfizer-BioNtech Comirnaty COVID-19 vaccine dose for people 12 years of age and older. VAERS data are restricted to vaccine antagonistic event stories obtained between 1990 and the most recent date for which data can be found. Produce tables, maps, charts, and information extracts of vaccine antagonistic occasions. VAERS information is accessible by downloading uncooked information in comma-separated worth recordsdata for import right into a database, spreadsheet, or textual content modifying program, or by utilizing the CDC WONDER on-line search device.

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