The ultimate primary limitation may be exclusion of ladies who took anti-emetics throughout pregnancy. This is as a result of the brink for nausea and vomiting where women sought and have been then prescribed anti-emetics would have diversified from participant to participant, and therefore the exclusion might have been somewhat self-selecting. However the advantage of doing this is the lack of potential confounding in our examine of those medicine affecting pathways concerned in regulating fetal growth, a strength of the research.

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